About telomeres

And why should you measure them

What are telomeres?

The body is a unit consisting of trillions of individual cells, functioning together. These cells consist of organelles, one of which is the nucleus of a cell. The nucleus then contains important structures, called¬†chromosomes, which are packages of genetic information, stored in the body and passed down from generations. The genetic information is quite simply a series of bases — Adenine (A), Guanine (G), Cytosine (C), and Thymine (T) — which form our “cellular alphabet,” containing the instructions used to create a human being.

Because an increase in telomerase expression increases telomere length, and telomerase activity is affected by lifestyle choices, knowledge on telomere length is considered actionable. This means that you can measure telomere length over time and make lifestyle decisions based on it.

Titanovo offers its telomere length testing kit at its online webstore. Our telomere testing kits show users the dynamics of their telomere length over time, as well as graphs which show users how their telomere length compares with users within and outside of their demographic group.

This information is then used to determine if they should make better lifestyle choices, such as eating healthier or exercising more often.

Telomere length Time Created with Snap

As we grow and age, the cells in our bodies are forced to duplicate, a process called mitosis; this is when one parent cell divides and forms two brand new daughter cells. Each time a cell divides, half of the genetic material goes to each individual daughter cell. Telomeres are the protective end-cap of a chromosome, which ensures that genetic information is successfully passed on from the parent cell to the daughter cells.

Specifically, the telomere is a repeating sequence of DNA at the end of the chromosome which can reach a length of 15,000 base pairs. Upon cell replication, telomeres prevent the chromosomes themselves from losing their base pair sequences. They also keep chromosomes from fusing with each other. On the other hand, with each division, up to 200 base pairs of DNA on the telomere are lost. Eventually, the telomere becomes critically short, which is called the “Hayflick Limit,” and cells cease to divide altogether; this is the cause of cell death.

Telomere length is controlled by both erosion and addition, with erosion happening when a cell divides and addition being determined by the enzyme telomerase. Telomerase consists of protein and RNA subunits which elongate telomeres by adding DNA base-pair sequences to the ends of chromosomes.

Because increased telomere length is associated with cellular lifetime and well-being, increased telomerase expression is key to living a long, healthy life.

Telomerase exhibition, meanwhile, has been shown to increase with healthy lifestyle choices, including meditation and exercise, proving a direct benefit to cellular health.

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