OE33Homo sapiens (Human)Cancer cell line
Also known as: OEC33, JROECL33, JROECL 33, OE-33
Quick Overview
OE33 is a human esophageal adenocarcinoma cell line used in cancer research.
Detailed Summary
Research Applications
Key Characteristics
Basic Information
| Database ID | CVCL_0471 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Esophagus[UBERON:UBERON_0001043] |
Donor Information
| Age | 73 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Adenocarcinoma of the esophagus |
|---|---|
| Lineage | Esophagus/Stomach |
| Subtype | Esophageal Adenocarcinoma |
| OncoTree Code | ESCA |
DepMap Information
| Source Type | HPACC |
|---|---|
| Source ID | ACH-000383_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Cys135Tyr (c.404G>A) | Unspecified | - | PubMed=21173094 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
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Publications
Pan-cancer proteomic map of 949 human cell lines.";
Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Cancer Cell 40:835-849.e8(2022).
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.
van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.
Nat. Commun. 10:3574.1-3574.11(2019).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Stronach E.A., Saez-Rodriguez J., Yusa K., Garnett M.J.
Nature 568:511-516(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Improved xenograft efficiency of esophageal adenocarcinoma cell lines through in vivo selection.
Ceelen W., Pattyn P.
Oncol. Rep. 38:71-81(2017).
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1.
Sharrocks A.D., Fitzgerald R.C., Underwood T.J.
Sci. Rep. 6:32417-32417(2016).
Whole-genome sequencing of nine esophageal adenocarcinoma cell lines.";
Lynch A.G., Edwards P.A.W., Fitzgerald R.C.
F1000Research 5:1336.1-1336.12(2016).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
Hypermethylation of MAPK13 promoter in oesophageal squamous cell carcinoma is associated with loss of p38delta MAPK expression.
O'Callaghan C., Fanning L.J., Barry O.P.
Cancers (Basel) 7:2124-2133(2015).
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Golub T.R., Root D.E., Hahn W.C.
Sci. Data 1:140035-140035(2014).
A resource for cell line authentication, annotation and quality control.
Neve R.M.
Nature 520:307-311(2015).
Translational research on esophageal adenocarcinoma: from cell line to clinic.
Boonstra J.J., Tilanus H.W., Dinjens W.N.M.
Dis. Esophagus 28:90-96(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).
Verification and unmasking of widely used human esophageal adenocarcinoma cell lines.
Shimada Y., van Dekken H., Tilanus H.W., Dinjens W.N.M.
J. Natl. Cancer Inst. 102:271-274(2010).
Gene expression profiling in human esophageal cancers using cDNA microarray.
Itami A., Yamasaki S., Imamura M.
Biochem. Biophys. Res. Commun. 286:792-801(2001).