SW13Homo sapiens (Human)Cancer cell line
Also known as: Scott and White No. 13, SW 13, SW-13
Quick Overview
Human adrenal tumor cell line for cancer research.
Detailed Summary
Research Applications
Key Characteristics
Basic Information
| Database ID | CVCL_0542 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Adrenal gland[UBERON:UBERON_0002369] |
Donor Information
| Age | 55 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Adrenocortical carcinoma |
|---|---|
| Lineage | Adrenal Gland |
| Subtype | Adrenocortical Carcinoma |
| OncoTree Code | ACC |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-001401_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.His193Tyr (c.577C>T) | Homozygous | - | PubMed=28736828 |
| MutationSimple | SMARCA4 | p.Gln164Ter (c.490C>T) | Heterozygous | - | from parent cell line SW13 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
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Publications
Pan-cancer proteomic map of 949 human cell lines.";
Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Cancer Cell 40:835-849.e8(2022).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
Comparison of aldosterone production among human adrenocortical cell lines.
Wang T., Rowland J.G., Parmar J., Nesterova M., Seki T., Rainey W.E.
Horm. Metab. Res. 44:245-250(2012).
Human adrenocortical carcinoma cell lines.";
Wang T., Rainey W.E.
Mol. Cell. Endocrinol. 351:58-65(2012).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).
Signatures of mutation and selection in the cancer genome.";
Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Nature 463:893-898(2010).
Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.
Wolf E., Gabius H.-J.
J. Cancer Res. Clin. Oncol. 127:375-386(2001).
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Rousset M., Zweibaum A., Fogh J.
Cancer Res. 41:1165-1170(1981).
A molecular approach to the identification and individualization of human and animal cells in culture: isozyme and allozyme genetic signatures.
O'Brien S.J., Shannon J.E., Gail M.H.
In Vitro 16:119-135(1980).
Role of p53 mutations in endocrine tumorigenesis: mutation detection by polymerase chain reaction-single strand conformation polymorphism.
Yoshimoto K., Iwahana H., Fukuda A., Sano T., Saito S., Itakura M.
Cancer Res. 52:5061-5064(1992).
Analysis of established human carcinoma cell lines for lymphoreticular-associated membrane receptors.
Kerbel R.S., Pross H.F., Leibovitz A.
Int. J. Cancer 20:673-679(1977).
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
Fogh J., Wright W.C., Loveless J.D.
J. Natl. Cancer Inst. 58:209-214(1977).
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
Fogh J., Fogh J.M., Orfeo T.
J. Natl. Cancer Inst. 59:221-226(1977).
Development of media for isolation and cultivation of human cancer cells.
Leibovitz A.
(In book chapter) Human tumor cells in vitro; Fogh J. (eds.); pp.23-50; Springer; New York; USA (1975).