SW1353Homo sapiens (Human)Cancer cell line
Also known as: SW 1353, SW-1353
Quick Overview
SW1353 is a chondrosarcoma cell line used in cancer research.
Detailed Summary
Research Applications
Key Characteristics
Basic Information
| Database ID | CVCL_0543 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Bone, right humerus[UBERON:UBERON_0000976] |
Donor Information
| Age | 72 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Chondrosarcoma |
|---|---|
| Lineage | Bone |
| Subtype | Chondrosarcoma |
| OncoTree Code | CHS |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000418_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Val203Leu (c.607G>C) | Heterozygous | - | Unknown, PubMed=19787792 |
| MutationSimple | IDH2 | p.Arg172Ser (c.516G>C) | Heterozygous | - | Unknown, PubMed=22057234 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Loading gene expression data...
Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Sister chromatid exchange and genomic instability in soft tissue sarcomas: potential implications for response to DNA-damaging treatments.
Salawu A., Wright K., Al-Kathiri A., Wyld L., Reed M.W.R., Sisley K.
Sarcoma 2018:3082526.1-3082526.8(2018).
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Bardeesy N.M.
Cancer Discov. 6:727-739(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Harris E., Monks A., Morris J.
Mol. Cancer Ther. 14:2452-2462(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.
Kurek K.C., Szuhai K., French P.J., Bovee J.V.M.G.
Nat. Genet. 43:1256-1261(2011).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).
Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort.
Buerger H., Aigner T., Gabbert H.E., Poremba C.
Genes Chromosomes Cancer 49:40-51(2010).
Comparison of the chondrosarcoma cell line SW1353 with primary human adult articular chondrocytes with regard to their gene expression profile and reactivity to IL-1beta.
Bartnik E., Beninga J., Zimmer R., Aigner T.
Osteoarthritis Cartilage 13:697-708(2005).
Development, availability and characterization of ATCC human and animal cell lines.
Hay R.J.
(In book chapter) Animal cell culture and production of biologicals; Sasaki R., Ikura K. (eds.); pp.27-39; Springer; Dordrecht; Netherlands (1991).