Hs 172.THomo sapiens (Human)Undefined cell line type
Also known as: HS172T, Hs172T, Hs-172-T
🤖 AI SummaryBased on 3 publications
Quick Overview
Human fibroblast cell line for cancer research.
Detailed Summary
Hs 172.T is a human fibroblast cell line derived from an unspecified tissue. It is commonly used in cancer research due to its fibroblast characteristics. The cell line is part of the Cancer Cell Line Encyclopedia (CCLE) and has been profiled in various genomic and pharmacological studies. Research involving Hs 172.T focuses on understanding cancer biology, drug sensitivity, and genetic predictors of treatment response. The cell line's utility in preclinical models highlights its importance in translational research.
Research Applications
Cancer researchDrug sensitivity profilingGenomic and pharmacological studies
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used in preclinical modelsFibroblast origin
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0660 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Urinary bladder[UBERON:UBERON_0001255] |
Donor Information
| Age | 50 |
|---|---|
| Age Category | Adult |
| Sex | Male |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000088_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
11,12
D13S317
12
D16S539
13
D5S818
11
D7S820
8,11
TH01
9.3
TPOX
9,11
vWA
18,21
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.
Bladder Cancer 4:169-183(2018).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).