Hs 255.THomo sapiens (Human)Undefined cell line type
Also known as: Hs255, HS255T, Hs255T, Hs-255-T
🤖 AI SummaryBased on 3 publications
Quick Overview
Human fibroblast cell line with potential applications in cancer research.
Detailed Summary
Hs 255.T is a human fibroblast cell line derived from an unspecified tissue. It is characterized by its ability to be used in various cancer-related studies, particularly in understanding the mechanisms of DNA repair and response to alkylating agents. This cell line has been utilized in research to investigate the effects of genotoxic agents on cellular processes and has shown sensitivity to certain chemotherapeutic agents. Its utility in studying DNA repair pathways and tumor response to treatment makes it a valuable resource for cancer research.
Research Applications
Cancer researchDNA repair mechanismsResponse to alkylating agents
Key Characteristics
Human fibroblastSensitivity to chemotherapeutic agentsPotential in DNA repair studies
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0707 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Colon[UBERON:UBERON_0001155] |
Donor Information
| Age | 46 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000199_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
11,12
D16S539
12,14
D18S51
13
D19S433
13.2,14
D21S11
28,32.2
D2S1338
19,27
D3S1358
14,15
D5S818
11
D7S820
8,14
D8S1179
16,17
FGA
24,27
Penta D
11,13
Penta E
11,12
TH01
8,9
TPOX
8,9
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
A resource for cell line authentication, annotation and quality control.
Neve R.M.
Nature 520:307-311(2015).
A comprehensive transcriptional portrait of human cancer cell lines.
Settleman J., Seshagiri S., Zhang Z.-M.
Nat. Biotechnol. 33:306-312(2015).
Human tumor cell strains defective in the repair of alkylation damage.
Mattern M.R.
Carcinogenesis 1:21-32(1980).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).