Hs 281.THomo sapiens (Human)Undefined cell line type
Also known as: HS281T, Hs281T, Hs-281-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer research
Detailed Summary
The Hs 281.T cell line is a human fibroblast derived from unknown tissue. It is used in cancer research, particularly in studies related to the Cancer Cell Line Encyclopedia (CCLE) which provides genomic and pharmacological data for drug sensitivity analysis. This cell line contributes to understanding cancer biology through its inclusion in large-scale genomic studies. Research applications include investigating genetic predictors of drug response and tumor heterogeneity.
Research Applications
Cancer researchGenomic studiesDrug sensitivity analysis
Key Characteristics
Human fibroblastPart of CCLEUsed in pharmacological profiling
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0715 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Breast[UBERON:UBERON_0000310] |
Donor Information
| Age | 37 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000083_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11
D13S317
8,12
D16S539
9,10
D5S818
9,13
D7S820
8,10
TH01
6,7
TPOX
11
vWA
17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).