Hs 343.THomo sapiens (Human)Undefined cell line type
Also known as: HS343T, Hs343T, Hs-343-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer research
Detailed Summary
Hs 343.T is a human fibroblast cell line derived from an unspecified tissue. It is used in cancer research, particularly in studies related to drug sensitivity and genomic profiling. The cell line is part of the Cancer Cell Line Encyclopedia (CCLE), which provides comprehensive genomic and pharmacological data for various cancer cell lines. This resource is valuable for understanding the genetic and molecular mechanisms underlying cancer and for developing targeted therapies. The CCLE includes data on gene expression, chromosomal copy number, and mutations, which can be used to identify predictors of drug response and to explore the relationship between genetic alterations and cancer progression.
Research Applications
Cancer researchDrug sensitivity studiesGenomic profiling
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used for pharmacological profilingIncludes genomic data for drug response prediction
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0726 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Breast[UBERON:UBERON_0000310] |
Donor Information
| Age | 47 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000184_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11
D13S317
8,12
D16S539
12
D18S51
16,21
D19S433
13,14
D21S11
28,29
D2S1338
17,24
D3S1358
16
D5S818
13
D7S820
7,10
D8S1179
12,13
FGA
20,21
Penta D
12,13
Penta E
12,13
TH01
9,9.3
TPOX
11
vWA
15,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).