Hs 600.THomo sapiens (Human)Undefined cell line type
Also known as: HS600T, Hs600T, Hs-600-T
🤖 AI SummaryBased on 3 publications
Quick Overview
Skin fibroblast cell line for cancer and genetic research.
Detailed Summary
Hs 600.T is a skin fibroblast cell line derived from human tissue. It is used in cancer research and genetic studies due to its fibroblast characteristics. The cell line is part of the Cancer Cell Line Encyclopedia (CCLE) and has been analyzed for genomic and pharmacological profiles. Research on this cell line focuses on understanding genetic variations and their implications in cancer development and treatment responses. The cell line's properties make it a valuable tool for studying tumor biology and drug sensitivity in preclinical models.
Research Applications
Cancer researchGenetic studiesPharmacological profiling
Key Characteristics
Skin fibroblast originPart of CCLE databaseUsed for genomic and drug sensitivity studies
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0814 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Skin[UBERON:UBERON_0002097] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Male |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000240_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
10,12
D13S317
11
D16S539
11,12
D18S51
13,18
D19S433
15,15.2
D21S11
30,31.2
D2S1338
23,25
D3S1358
15
D5S818
11,12
D7S820
8,9
D8S1179
13,14
FGA
20.2,22
Penta D
9,10
Penta E
5,7
TH01
7,9.3
TPOX
8
vWA
17,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).