Hs 606.THomo sapiens (Human)Undefined cell line type
Also known as: Hs606, Hs 606, HS606T, Hs606T, Hs-606-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human cell line for cancer research and drug testing.
Detailed Summary
Hs 606.T is a human cell line used in cancer research and drug testing. It is part of the Cancer Cell Line Encyclopedia (CCLE) and the Catalogue of Somatic Mutations in Cancer (COSMIC) databases, which provide extensive genomic and pharmacological data. The cell line is utilized in studies involving drug sensitivity and resistance, contributing to the understanding of cancer biology and the development of targeted therapies. Research applications include the identification of genetic predictors of drug response and the exploration of molecular mechanisms underlying cancer progression. The cell line's genomic and pharmacological profiles are valuable for preclinical studies and personalized medicine approaches.
Research Applications
Cancer researchDrug testingDrug sensitivity and resistance studiesGenetic predictors of drug responseMolecular mechanisms of cancer progressionPreclinical studiesPersonalized medicine
Key Characteristics
Part of CCLE and COSMIC databasesGenomic and pharmacological data availableUsed in drug sensitivity and resistance researchContributes to cancer biology understandingSupports targeted therapy development
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0819 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age | 44 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000540_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11,12
D13S317
9,12
D16S539
11,12
D18S51
13,14
D19S433
14
D21S11
30,33.2
D2S1338
22,23
D3S1358
15
D5S818
11,13
D7S820
8,10
D8S1179
15
FGA
19,23
Penta D
9,12
Penta E
5,22
TH01
7,9
TPOX
8
vWA
14,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).