Hs 611.THomo sapiens (Human)Cancer cell line

Also known as: HS611T, Hs611T, Hs-611-T

🤖 AI SummaryBased on 2 publications

Quick Overview

Human cell line for cancer research and drug sensitivity studies.

Detailed Summary

The Hs 611.T cell line is a human-derived cell line utilized in cancer research, particularly in studies related to drug sensitivity and genomic profiling. While specific details about its tissue origin, disease type, and cell type are not explicitly provided in the available data, the cell line is part of broader cancer research initiatives, such as the Cancer Cell Line Encyclopedia (CCLE), which aims to characterize the genetic and pharmacological profiles of cancer cell lines. This cell line may be used to investigate the relationship between genetic mutations and drug response, contributing to the development of personalized cancer therapies. Further research is needed to fully understand its biological properties and applications.

Research Applications

Cancer researchDrug sensitivity studiesGenomic profiling

Key Characteristics

Human-derivedPart of CCLEPotential for drug response analysis
Generated on 6/15/2025

Basic Information

Database IDCVCL_0823
SpeciesHomo sapiens (Human)
Tissue SourceLymph node[UBERON:UBERON_0000029]

Donor Information

Age48
Age CategoryAdult
SexFemale

Disease Information

DiseaseHodgkin lymphoma
LineageLymphoid
SubtypeHodgkin Lymphoma
OncoTree CodeHL

DepMap Information

Source TypeATCC
Source IDACH-000069_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
9,11
D13S317
11
D16S539
12
D18S51
12,13
D19S433
12,16
D21S11
30
D2S1338
16,24
D3S1358
14,17
D5S818
11
D7S820
8,10
D8S1179
13,14
FGA
21,22
Penta D
9,11
Penta E
10,12
TH01
6,9
TPOX
8,9
vWA
15,16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.

Yang H.H., Koeffler H.P.

BMC Cancer 18:940.1-940.13(2018).

High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project.

O'Grady T., Baddoo M., Fewell C., Renne R., Flemington E.K.

J. Virol. 89:713-729(2015).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).