Hs 688(A).THomo sapiens (Human)Undefined cell line type

Also known as: HS688AT, Hs-688A-T, Hs688(A)T

🤖 AI SummaryBased on 2 publications

Quick Overview

Human skin fibroblast cell line for research.

Detailed Summary

The Hs 688(A).T cell line is derived from human skin fibroblasts. It is commonly used in research applications related to skin biology, fibroblast function, and disease modeling. As a fibroblast cell line, it provides a valuable model for studying cellular processes such as proliferation, differentiation, and response to environmental factors. While specific research applications are not detailed in the available data, its utility in in vitro studies of skin-related conditions is implied by its cell type. Further characterization may be required to determine its suitability for specific experimental contexts.

Research Applications

Skin biology researchFibroblast function studiesDisease modeling

Key Characteristics

Human-derivedSkin fibroblast origin
Generated on 6/15/2025

Basic Information

Database IDCVCL_0846
SpeciesHomo sapiens (Human)
Tissue SourceSkin[UBERON:UBERON_0002097]

Donor Information

Age69
Age CategoryAdult
SexMale
Racecaucasian

Disease Information

DiseaseNon-Cancerous
LineageFibroblast
SubtypeFibroblast, Soft Tissue

DepMap Information

Source TypeATCC
Source IDACH-000306_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
10,12
D13S317
12,13
D16S539
9,13
D18S51
19
D19S433
12
D21S11
28,31.2
D2S1338
18,20
D3S1358
16,17
D5S818
8,11
D7S820
10,11
D8S1179
12,13
FGA
23,26
Penta D
12,14
Penta E
5,10
TH01
7,9
TPOX
8,11
vWA
15,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Fibroblasts cell lines misclassified as cancer cell lines.";

de Weck A., Bitter H., Kauffmann A.

bioRxiv 2017:166199-166199(2017).