Hs 698.THomo sapiens (Human)Undefined cell line type
Also known as: HS698T, Hs698T, Hs-698-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer research
Detailed Summary
Hs 698.T is a human fibroblast cell line that has been utilized in cancer research. It is part of the Cancer Cell Line Encyclopedia (CCLE) and the Catalogue of Somatic Mutations in Cancer (COSMIC) databases, which provide comprehensive genomic and pharmacological profiles for various cancer cell lines. The cell line's genetic and molecular characteristics are valuable for studying cancer biology, drug sensitivity, and therapeutic strategies. However, specific details about its tissue origin, disease context, and precise research applications remain unspecified in the available data.
Research Applications
Cancer researchDrug sensitivity studiesGenomic profiling
Key Characteristics
Part of CCLE and COSMIC databasesHuman fibroblast origin
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0855 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Connective tissue[UBERON:UBERON_0002384] |
Donor Information
| Age | 70 |
|---|---|
| Age Category | Adult |
| Sex | Male |
| Race | american_indian_or_native_american |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000850_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
11,13
D13S317
11,12
D16S539
12
D18S51
15,18
D19S433
13,15.2
D21S11
32.2
D2S1338
20,21
D3S1358
15,16
D5S818
10,11
D7S820
8,10
D8S1179
11,13
FGA
19,23
Penta D
9,12
Penta E
16,17
TH01
8,9
TPOX
8,11
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).