Hs 739.THomo sapiens (Human)Undefined cell line type
Also known as: HS739T, Hs739T, Hs-739-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer research.
Detailed Summary
Hs 739.T is a human fibroblast cell line derived from unknown tissue. It is used in cancer research, particularly in studies involving the Cancer Cell Line Encyclopedia (CCLE) and the Cancer Genome Atlas (TCGA). This cell line is part of a large collection of cancer cell lines that provide genomic and pharmacological data for drug sensitivity studies. The CCLE and TCGA projects have contributed to the understanding of cancer biology and the development of targeted therapies. Hs 739.T is one of the many cell lines used to study the genetic and molecular mechanisms underlying cancer progression and treatment response.
Research Applications
Cancer researchDrug sensitivity studiesGenomic and pharmacological profiling
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used in the Cancer Genome Atlas (TCGA) projectsProvides genomic and pharmacological data for drug sensitivity
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0882 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Breast[UBERON:UBERON_0000310] |
Donor Information
| Age | 52 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
8,9
D16S539
9,12
D5S818
13
D7S820
11
TH01
9
TPOX
8,9
vWA
14,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).