Hs 742.THomo sapiens (Human)Undefined cell line type
Also known as: HS742T, Hs742T, Hs-742-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer research
Detailed Summary
Hs 742.T is a human fibroblast cell line derived from unknown tissue. It is used in cancer research, particularly in studies involving the Cancer Cell Line Encyclopedia (CCLE) and the Cancer Genome Atlas (TCGA). The cell line has been characterized for its genomic and pharmacological profiles, contributing to the understanding of drug sensitivity and resistance mechanisms in cancer. Its role in identifying genetic predictors of drug response has been highlighted in several studies.
Research Applications
Cancer researchDrug sensitivity profilingGenomic and pharmacological profiling
Key Characteristics
Human fibroblastUsed in CCLE and TCGA studiesGenomic and pharmacological characterization
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0888 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Breast[UBERON:UBERON_0000310] |
Donor Information
| Age | 71 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000230_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
9,12
D16S539
11,12
D18S51
18,19
D19S433
13,14
D21S11
30,31
D2S1338
17
D3S1358
15,17
D5S818
12
D7S820
8,9
D8S1179
12,13
FGA
22,25
Penta D
12,13
Penta E
11
TH01
6,9.3
TPOX
8
vWA
17,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).