Hs 751.THomo sapiens (Human)Undefined cell line type
Also known as: HS751T, Hs751T
🤖 AI SummaryBased on 3 publications
Quick Overview
Human fibroblast cell line for cancer and genetic research.
Detailed Summary
Hs 751.T is a human fibroblast cell line derived from unknown tissue. It is used in cancer and genetic research, particularly in studies involving genomic diversity and cancer disparities. The cell line is part of large-scale cancer cell line databases like the Cancer Cell Line Encyclopedia (CCLE) and the Catalogue of Somatic Mutations in Cancer (COSMIC). These resources help in understanding the genetic basis of cancer and in developing targeted therapies. Hs 751.T is also utilized in studies examining the impact of genetic ancestry on cancer research and treatment outcomes.
Research Applications
Cancer researchGenetic researchGenomic diversity studiesCancer disparities research
Key Characteristics
Part of large cancer cell line databasesUsed in studies on genetic ancestry and cancer
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0891 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Lymph node[UBERON:UBERON_0000029] |
Donor Information
| Age | 19 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000165_source |
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).