Hs 840.THomo sapiens (Human)Undefined cell line type
Also known as: HS840T, Hs840T, Hs840_T, Hs-840-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer and drug sensitivity studies.
Detailed Summary
Hs 840.T is a human fibroblast cell line derived from a normal tissue source. It is part of the Cancer Cell Line Encyclopedia (CCLE) and has been used in studies related to cancer research and drug sensitivity profiling. The cell line provides a platform for investigating genetic and molecular characteristics associated with cancer progression and therapeutic responses. While specific disease information is not available, its fibroblast origin suggests potential applications in studying tumor microenvironments and cellular interactions. The cell line's inclusion in large-scale genomic and pharmacological datasets highlights its utility in preclinical research and drug discovery efforts.
Research Applications
Cancer researchDrug sensitivity profilingGenomic and pharmacological studies
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used in preclinical drug discoveryRelevant for studying tumor microenvironments
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0942 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Pharynx[UBERON:UBERON_0006562] |
Donor Information
| Age | 7 |
|---|---|
| Age Category | Pediatric |
| Sex | Male |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000284_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
11,12
D13S317
12
D16S539
11,13
D18S51
13,19
D19S433
13,15
D21S11
31,32
D2S1338
21,23
D3S1358
15,17
D5S818
11,12
D7S820
8,11
D8S1179
13,15
FGA
19,22
Penta D
9,13
Penta E
12,13
TH01
6
TPOX
8,9
vWA
15
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).