Hs 863.THomo sapiens (Human)Undefined cell line type
Also known as: HS863T, Hs863T, Hs-863-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer research
Detailed Summary
The Hs 863.T cell line is a human fibroblast derived from unknown tissue. It is used in cancer research, particularly in studies related to the Cancer Cell Line Encyclopedia (CCLE) which provides genomic and pharmacological data for drug sensitivity analysis. This cell line contributes to understanding genetic predictors of drug response and cancer biology through large-scale genomic profiling and pharmacological screening. Its role in the CCLE highlights its importance in preclinical cancer research and the development of targeted therapies.
Research Applications
Cancer researchDrug sensitivity analysisGenomic profilingPharmacological screening
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used for understanding genetic predictors of drug responseContributes to preclinical cancer research
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0959 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Bone[UBERON:UBERON_0002481] |
Donor Information
| Age | 5 |
|---|---|
| Age Category | Pediatric |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000119_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12,13
D13S317
11,12
D16S539
11
D18S51
15,16
D19S433
15
D21S11
28,29
D2S1338
24,25
D3S1358
15,17
D5S818
11,12
D7S820
8,13
D8S1179
13,14
FGA
20,24
Penta D
9,12
Penta E
7,16
TH01
7
TPOX
8
vWA
14,15
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).