Hs 870.THomo sapiens (Human)Undefined cell line type
Also known as: HS870T, Hs870T, Hs-870-T
🤖 AI SummaryBased on 2 publications
Quick Overview
Human fibroblast cell line for cancer research
Detailed Summary
Hs 870.T is a human fibroblast cell line derived from unknown tissue. It is used in cancer research, particularly in studies related to drug sensitivity and genomic profiling. The cell line is part of large-scale cancer cell line databases, contributing to the understanding of cancer biology and therapeutic strategies. Its role in research includes the analysis of genetic and molecular characteristics that influence drug responses and tumor behavior. The cell line's utility is supported by its inclusion in comprehensive datasets that facilitate the identification of biomarkers and predictive models for cancer treatment.
Research Applications
Cancer researchDrug sensitivity analysisGenomic profiling
Key Characteristics
Human fibroblastPart of large-scale cancer cell line databasesUsed in drug response and tumor behavior studies
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0966 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Bone[UBERON:UBERON_0002481] |
Donor Information
| Age | 22 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000340_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg110Pro (c.329G>C) | Heterozygous | - | from parent cell line S462 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
10,13
D13S317
11,13
D16S539
9,13
D18S51
13,19
D19S433
10,16
D21S11
31.2,32.2
D2S1338
18
D3S1358
17,18
D5S818
10,12
D7S820
9,11
D8S1179
14
FGA
18.2,22
Penta D
10,12
Penta E
12,13
TH01
7,9.3
TPOX
8,11
vWA
16,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).