Hs 888.THomo sapiens (Human)Undefined cell line type

Also known as: HS888T, Hs888T, Hs-888-T

🤖 AI SummaryBased on 2 publications

Quick Overview

Human lung fibroblast cell line for cancer research

Detailed Summary

The Hs 888.T cell line is a human lung fibroblast derived from normal tissue. It is commonly used in cancer research due to its fibroblast characteristics. This cell line provides a valuable model for studying lung-related diseases and drug responses. Its fibroblast origin makes it suitable for investigating cellular mechanisms in both healthy and diseased states.

Research Applications

cancer researchdrug response studieslung disease modeling
Generated on 6/15/2025

Basic Information

Database IDCVCL_0979
SpeciesHomo sapiens (Human)
Tissue SourceLung[UBERON:UBERON_0002048]

Donor Information

Age20
Age CategoryAdult
SexMale
Racecaucasian

Disease Information

DiseaseNon-Cancerous
LineageFibroblast
SubtypeFibroblast, Soft Tissue

DepMap Information

Source TypeATCC
Source IDACH-000154_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X,Y
CSF1PO
10,11
D13S317
11,14
D16S539
8,12
D18S51
13,16
D19S433
13,14
D21S11
28,29
D2S1338
19,20
D3S1358
16,18
D5S818
13
D7S820
7,11
D8S1179
14,16
FGA
21,23
Penta D
13
Penta E
13,19
TH01
9.3,10
TPOX
8,11
vWA
15,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Fibroblasts cell lines misclassified as cancer cell lines.";

de Weck A., Bitter H., Kauffmann A.

bioRxiv 2017:166199-166199(2017).