Hs 895.THomo sapiens (Human)Undefined cell line type
Also known as: HS895T, Hs895T, Hs895.T, Hs 895 T, Hs-895-T
🤖 AI SummaryBased on 6 publications
Quick Overview
Human skin fibroblast cell line for cancer research
Detailed Summary
Hs 895.T is a human skin fibroblast cell line used in cancer research. It is part of a comprehensive collection of cancer cell lines that have been analyzed for their genomic and transcriptomic profiles. This cell line has been included in studies examining gene expression, mutations, and fusion events that may contribute to cancer development and progression. Research on Hs 895.T has provided insights into the molecular mechanisms underlying cancer, including the identification of potential biomarkers and therapeutic targets. The cell line is also used to study the impact of genetic variations on drug response and cancer biology.
Research Applications
Cancer researchGenomic and transcriptomic analysisDrug response studiesBiomarker identification
Key Characteristics
Human skin fibroblastUsed in cancer studiesPart of large cell line collectionsAnalyzed for gene expression and mutations
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0993 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Skin[UBERON:UBERON_0002097] |
Donor Information
| Age | 48 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | caucasian |
Disease Information
| Disease | Non-Cancerous |
|---|---|
| Lineage | Fibroblast |
| Subtype | Fibroblast, Soft Tissue |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000043_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11
D13S317
12
D16S539
12,14
D18S51
12,15
D19S433
12,13
D21S11
30,31
D2S1338
17,19
D3S1358
17,18
D5S818
11,12
D7S820
10,12
D8S1179
13,15
FGA
19,25
Penta D
11,12
Penta E
7,17
TH01
6,7
TPOX
8,11
vWA
18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Signatures of protein expression revealed by secretome analyses of cancer associated fibroblasts and melanoma cell lines.
Zelanis A.
J. Proteomics 174:1-8(2018).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
A resource for cell line authentication, annotation and quality control.
Neve R.M.
Nature 520:307-311(2015).
A comprehensive transcriptional portrait of human cancer cell lines.
Settleman J., Seshagiri S., Zhang Z.-M.
Nat. Biotechnol. 33:306-312(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).
Fibroblasts cell lines misclassified as cancer cell lines.";
de Weck A., Bitter H., Kauffmann A.
bioRxiv 2017:166199-166199(2017).