ZN-RCapra hircus (Goat)Finite cell line
Also known as: ZN-R1
🤖 AI SummaryBased on 2 publications
Quick Overview
Capra hircus cell line for virology research
Detailed Summary
The ZN-R cell line, derived from Capra hircus (goat), is utilized in virology studies. It has been characterized for its ability to support viral replication, particularly showing permissiveness to MERS-CoV. This cell line is part of a collection used for authenticating and studying animal cell cultures. The ZN-R cell line is a primary cell type, originating from the kidney tissue. It has been employed in research to assess the replication capacity of various viruses, including MERS-CoV, demonstrating significant viral replication in goat kidney cells. The cell line's utility in virological research is supported by its consistent expression of the DPP-4 receptor, which is crucial for MERS-CoV infection. Additionally, ZN-R has been used in studies to evaluate the effectiveness of quality control methods for cell cultures, such as MALDI-TOF mass spectrometry for authentication.
Research Applications
VirologyViral replication studiesCell culture authenticationMERS-CoV research
Key Characteristics
Expresses DPP-4 receptorSupports MERS-CoV replicationUsed in quality control assessments
Generated on 6/15/2025
Basic Information
| Database ID | CVCL_0I67 |
|---|---|
| Species | Capra hircus (Goat) |
| Tissue Source | Kidney[UBERON:UBERON_0002113] |
Disease Information
DepMap Information
Publications
Replicative capacity of MERS coronavirus in livestock cell lines.";
Drosten C.
Emerg. Infect. Dis. 20:276-279(2014).