Hs 934.THomo sapiens (Human)Undefined cell line type

Also known as: HS934T, Hs934T, Hs-934-T

🤖 AI SummaryBased on 2 publications

Quick Overview

Human fibroblast cell line for cancer research.

Detailed Summary

Hs 934.T is a human fibroblast cell line derived from a tumor tissue. It is used in cancer research to study tumor biology and drug sensitivity. The cell line is part of the Cancer Cell Line Encyclopedia (CCLE), which provides genomic and pharmacological data for preclinical studies. Research applications include identifying genetic predictors of drug response and understanding tumor heterogeneity. The cell line's properties are characterized by its fibroblast origin and its role in high-throughput screening and molecular profiling.

Research Applications

Cancer researchDrug sensitivity profilingGenomic and pharmacological data analysisTumor heterogeneity studies

Key Characteristics

Human fibroblast originPart of the Cancer Cell Line Encyclopedia (CCLE)Used in high-throughput screeningMolecular profiling for drug response prediction
Generated on 6/16/2025

Basic Information

Database IDCVCL_1031
SpeciesHomo sapiens (Human)
Tissue SourceConnective tissue[UBERON:UBERON_0002384]

Donor Information

Age58
Age CategoryAdult
SexFemale
Racecaucasian

Disease Information

DiseaseNon-Cancerous
LineageFibroblast
SubtypeFibroblast, Soft Tissue

DepMap Information

Source TypeATCC
Source IDACH-000194_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
10,11
D13S317
10,11
D16S539
12
D5S818
11
D7S820
11,12
TH01
7,8
TPOX
8
vWA
16,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Fibroblasts cell lines misclassified as cancer cell lines.";

de Weck A., Bitter H., Kauffmann A.

bioRxiv 2017:166199-166199(2017).