Hs 936.THomo sapiens (Human)Cancer cell line
Also known as: HS936T, Hs936T, Hs936.T, Hs-936.T, HS 936T, HS 936.T, Hs-936-T
🤖 AI SummaryBased on 6 publications
Quick Overview
Human cancer cell line with unknown tissue and disease origins.
Detailed Summary
Hs 936.T is a human cancer cell line with unknown tissue and disease origins. It is part of a large collection of cancer cell lines used for research, including studies on genomic and transcriptomic diversity. The cell line has been included in comprehensive analyses of cancer cell line characteristics, such as those published in 'A comprehensive transcriptional portrait of human cancer cell lines' and 'The Cancer Cell Line Encyclopedia'. These studies have identified various genetic and molecular features, including gene fusions, mutations, and expression profiles, which are critical for understanding cancer biology and developing targeted therapies. However, specific details about the tissue of origin and disease type for Hs 936.T are not available in the provided data.
Generated on 6/16/2025
Basic Information
| Database ID | CVCL_1033 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Skin[UBERON:UBERON_0002097] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Male |
Disease Information
| Disease | Melanoma |
|---|---|
| Lineage | Skin |
| Subtype | Melanoma |
| OncoTree Code | MEL |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000801_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | NRAS | p.Gln61Lys (c.181C>A) | Unspecified | Acquired during resistance selection process | PubMed=26214590 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
8,12
D13S317
8
D16S539
9,12
D5S818
9,12
D7S820
8,11
TH01
7,9.3
TPOX
8
vWA
17,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
A comprehensive transcriptional portrait of human cancer cell lines.
Settleman J., Seshagiri S., Zhang Z.-M.
Nat. Biotechnol. 33:306-312(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).