A-204Homo sapiens (Human)Cancer cell line
Also known as: A204, HTB82 (Based on the ATCC catalog number.)
Quick Overview
Human rhabdomyosarcoma cell line for cancer research
Detailed Summary
Research Applications
Key Characteristics
Basic Information
| Database ID | CVCL_1058 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Muscle[UBERON:UBERON_0001630] |
Donor Information
| Age | 1 |
|---|---|
| Age Category | Pediatric |
| Sex | Female |
Disease Information
| Disease | Embryonal rhabdomyosarcoma |
|---|---|
| Lineage | Kidney |
| Subtype | Rhabdoid Cancer |
| OncoTree Code | MRT |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000201_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | SMARCB1 | p.Gln182Alafs*28 (c.543_544delTC) | Heterozygous | - | from parent cell line A-204 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Loading gene expression data...
Publications
Pan-cancer proteomic map of 949 human cell lines.";
Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Cancer Cell 40:835-849.e8(2022).
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib.
Huang P.H.
J. Proteomics 170:130-140(2018).
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
Sarcoma cell line screen of oncology drugs and investigational agents identifies patterns associated with gene and microRNA expression.
Harris E., Monks A., Morris J.
Mol. Cancer Ther. 14:2452-2462(2015).
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.
Golub T.R., Root D.E., Hahn W.C.
Sci. Data 1:140035-140035(2014).
Human rhabdomyosarcoma cell lines for rhabdomyosarcoma research: utility and pitfalls.
Linardic C.M.
Front. Oncol. 3:183.1-183.12(2013).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).
Immunocytochemical analysis of cell lines derived from solid tumors.
Quentmeier H., Osborn M., Reinhardt J., Zaborski M., Drexler H.G.
J. Histochem. Cytochem. 49:1369-1378(2001).
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors.
DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.
Oncogene 18:7559-7565(1999).
Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays.
Smith P.D., Jiang Y., Gooden G.C., Trent J.M., Meltzer P.S.
Cancer Res. 58:5009-5013(1998).
Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma.
Rauscher F.J. 3rd, Emanuel B.S., Rovera G., Barr F.G.
Nat. Genet. 5:230-235(1993).
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors.
Dosik H., Parks W.P.
J. Natl. Cancer Inst. 51:1417-1423(1973).
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.
Cancer Res. 48:589-601(1988).
In vitro purging of human rhabdomyosarcoma cells using 4-hydroperoxycyclophosphamide.
Ozkaynak M.F., Nolta J., Parkman R.
Cancer Res. 50:1455-1458(1990).
Platelet-derived growth factor (PDGF) receptor activation in cell transformation and human malignancy.
Fleming T.P., Matsui T., Aaronson S.A.
Exp. Gerontol. 27:523-532(1992).
Absence of HeLa cell contamination in 169 cell lines derived from human tumors.
Fogh J., Wright W.C., Loveless J.D.
J. Natl. Cancer Inst. 58:209-214(1977).
Human brain tumour cell strains with deficient host-cell reactivation of N-methyl-N'-nitro-N-nitrosoguanidine-damaged adenovirus 5.
Day R.S. 3rd, Ziolkowski C.H.J.
Nature 279:797-799(1979).
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
Fogh J., Fogh J.M., Orfeo T.
J. Natl. Cancer Inst. 59:221-226(1977).
Growth factors produced by sarcoma virus-transformed cells.";
Todaro G.J., De Larco J.E.
Cancer Res. 38:4147-4154(1978).