CHP-126Homo sapiens (Human)Cancer cell line
Also known as: Children's Hospital of Philadelphia-126, CHP126, CHP 126
Quick Overview
Human neuroblastoma cell line with HSR and DM abnormalities
Detailed Summary
Research Applications
Key Characteristics
Basic Information
| Database ID | CVCL_1123 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Retroperitoneal space[UBERON:UBERON_0003693] |
Donor Information
| Age | 1 |
|---|---|
| Age Category | Pediatric |
| Sex | Female |
| Subtype Features | MYC_Amplified |
Disease Information
| Disease | Neuroblastoma |
|---|---|
| Lineage | Peripheral Nervous System |
| Subtype | Neuroblastoma |
| OncoTree Code | NBL |
DepMap Information
| Source Type | DSMZ |
|---|---|
| Source ID | ACH-000136_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
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Publications
Pan-cancer proteomic map of 949 human cell lines.";
Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Cancer Cell 40:835-849.e8(2022).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
A resource for cell line authentication, annotation and quality control.
Neve R.M.
Nature 520:307-311(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Signatures of mutation and selection in the cancer genome.";
Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Nature 463:893-898(2010).
Mutations in PIK3CA are infrequent in neuroblastoma.";
Dam V., Morgan B.T., Mazanek P., Hogarty M.D.
BMC Cancer 6:177.1-177.10(2006).
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma.
Maris J.M.
Genes Chromosomes Cancer 43:390-403(2005).
Immunocytochemical analysis of cell lines derived from solid tumors.
Quentmeier H., Osborn M., Reinhardt J., Zaborski M., Drexler H.G.
J. Histochem. Cytochem. 49:1369-1378(2001).
Short tandem repeat profiling provides an international reference standard for human cell lines.
Harrison M., Virmani A.K., Ward T.H., Ayres K.L., Debenham P.G.
Proc. Natl. Acad. Sci. U.S.A. 98:8012-8017(2001).
Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines.
Schlesinger H.R.
Cancer Genet. Cytogenet. 7:33-42(1982).
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.
Gilbert F., Brodeur G.M., Goldstein M.N., Trent J.M.
Nature 305:245-248(1983).
Neuronal properties of neuroectodermal tumors in vitro.";
Schlesinger H.R., Rorke-Adams L.B., Jamieson R., Hummeler K.
Cancer Res. 41:2573-2575(1981).
Expression of N-myc, c-myc, and MDR-1 proteins in newly established neuroblastoma cell lines: a study by immunofluorescence staining and flow cytometry.
Gazitt Y., He Y.-J., Chang L., Koza S., Fisk D., Graham-Pole J.
Cancer Res. 52:2957-2965(1992).
Double minute chromosomes and the homogeneously staining regions in chromosomes of a human neuroblastoma cell line.
Balaban-Malenbaum G.B., Gilbert F.
Science 198:739-741(1977).
Isolation and characterization of a neuroblastoma cell line from peripheral blood in a patient with disseminated disease.
Gerson J.M., Schlesinger H.R., Sereni P., Moorhead P.S., Hummeler K.
Cancer 39:2508-2512(1977).
Establishment and characterization of human neuroblastoma cell lines.
Schlesinger H.R., Gerson J.M., Moorhead P.S., Maguire H., Hummeler K.
Cancer Res. 36:3094-3100(1976).
Tumor cell lines of the peripheral nervous system.";
Israel M.A., Thiele C.J.
(In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.43-78; Academic Press; New York; USA (1994).
Homogeneously staining regions and double minute chromosomes, prevalent cytogenetic abnormalities of human neuroblastoma cells.
Biedler J.L., Meyers M.B., Spengler B.A.
(In book chapter) Advances in cellular neurobiology, Vol. 4; Fedoroff S., Hertz L. (eds.); pp.267-307; Academic Press; New York; USA (1983).
Neuroblastoma.";
Thiele C.J.
(In book chapter) Human cell culture. Vol. 1. Cancer cell lines part 1; Masters J.R.W., Palsson B.O. (eds.); pp.21-53; Kluwer Academic Publishers; New York; USA (1999).