COLO 792Homo sapiens (Human)Cancer cell line

Also known as: Colorado 792, COLO792, COLO #792, COLO-792

🤖 AI SummaryBased on 6 publications

Quick Overview

Human cancer cell line with unknown tissue and disease origin.

Detailed Summary

COLO 792 is a human cancer cell line with unknown tissue and disease origins. It is part of a large collection of cancer cell lines used for research, but specific details about its tissue of origin, disease type, and cell type are not provided in the available data. The cell line is included in studies that analyze genomic and transcriptomic features of cancer cell lines, such as the identification of gene fusions and mutations. However, without specific information on its origin, its use in targeted research applications may be limited. Further characterization is needed to determine its potential as a model for specific cancer types or therapeutic studies.

Research Applications

Genomic and transcriptomic analysis of cancer cell linesIdentification of gene fusions and mutations

Key Characteristics

Part of a large panel of cancer cell linesUsed in studies of cancer genomics and drug sensitivity

Generated on 6/16/2025

Basic Information

Database ID	CVCL_1134
Species	Homo sapiens (Human)
Tissue Source	Brain[UBERON:UBERON_0000955]

Donor Information

Age	62
Age Category	Adult
Sex	Male

Disease Information

Disease	Melanoma
Lineage	Skin
Subtype	Melanoma
OncoTree Code	MEL

DepMap Information

Source Type	ECACC
Source ID	ACH-000968_source

Known Sequence Variations

Type	Gene/Protein	Description	Zygosity	Note	Source
MutationSimple	TERT	c.1-124C>T (c.228C>T) (C228T)	Unspecified	In promoter	from parent cell line Hep-G2
MutationSimple	ARID2	p.Arg274Ter (c.820C>T)	Heterozygous	-	Unknown, Unknown

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin

X,Y

CSF1PO

D13S317

11,12

D16S539

D18S51

13,17

D21S11

28,32.2

D3S1358

D5S818

10,12

D7S820

10,11

D8S1179

13,16

FGA

18,21

Penta D

8,13

Penta E

TH01

6,9

TPOX

8,11

vWA

16,17

Gene Expression Profile

Gene expression levels and statistical distribution

Loading cohorts...

Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

Pan-cancer proteomic map of 949 human cell lines.";

Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

Cancer Cell 40:835-849.e8(2022).

DOI PubMed PMC

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

DOI PubMed PMC

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

DOI PubMed PMC

A landscape of pharmacogenomic interactions in cancer.";

Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

Cell 166:740-754(2016).

DOI PubMed PMC

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

DOI PubMed PMC

A resource for cell line authentication, annotation and quality control.

Neve R.M.

Nature 520:307-311(2015).

DOI PubMed

A comprehensive transcriptional portrait of human cancer cell lines.

Settleman J., Seshagiri S., Zhang Z.-M.

Nat. Biotechnol. 33:306-312(2015).

DOI PubMed

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

DOI PubMed PMC

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Haber D.A.

Cancer Res. 70:2158-2164(2010).

DOI PubMed PMC

Signatures of mutation and selection in the cancer genome.";

Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Nature 463:893-898(2010).

DOI PubMed PMC

Protein B61 as a new growth factor: expression of B61 and up-regulation of its receptor epithelial cell kinase during melanoma progression.

Toso R.J., Herlyn M., Bennett D.C.

Cancer Res. 55:2528-2532(1995).

PubMed