EHEBHomo sapiens (Human)Transformed cell line
Quick Overview
EHEB is a human B-cell chronic lymphocytic leukemia cell line with normal karyotype and Ig gene rearrangements.
Detailed Summary
Research Applications
Key Characteristics
Basic Information
| Database ID | CVCL_1194 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Donor Information
| Age | 69 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | B-Lymphoblastic Leukemia/Lymphoma |
|---|---|
| Lineage | Lymphoid |
| Subtype | B-Lymphoblastic Leukemia/Lymphoma |
| OncoTree Code | BLL |
DepMap Information
| Source Type | DSMZ |
|---|---|
| Source ID | ACH-000038_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Screening human cell lines for viral infections applying RNA-Seq data analysis.
Uphoff C.C., Pommerenke C., Denkmann S.A., Drexler H.G.
PLoS ONE 14:E0210404-E0210404(2019).
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
Yang H.H., Koeffler H.P.
BMC Cancer 18:940.1-940.13(2018).
Characterization of human cancer cell lines by reverse-phase protein arrays.
Liang H.
Cancer Cell 31:225-239(2017).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
Molecular characterization of neoplastic and normal 'sister' lymphoblastoid B-cell lines from chronic lymphocytic leukemia.
Jurlander J., Klein E., Weit N., Herling M., Rosenquist R., Rosen A.
Leuk. Lymphoma 54:1769-1779(2013).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Detection of EBV, HBV, HCV, HIV-1, HTLV-I and -II, and SMRV in human and other primate cell lines.
Uphoff C.C., Denkmann S.A., Steube K.G., Drexler H.G.
J. Biomed. Biotechnol. 2010:904767.1-904767.23(2010).
Signatures of mutation and selection in the cancer genome.";
Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Nature 463:893-898(2010).
False leukemia-lymphoma cell lines: an update on over 500 cell lines.
Drexler H.G., Dirks W.G., Matsuo Y., MacLeod R.A.F.
Leukemia 17:416-426(2003).
Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.
Ferrant A., Van den Berghe G., Bontemps F.
Clin. Cancer Res. 7:3559-3566(2001).
Establishment of a karyotypically normal B-chronic lymphocytic leukemia cell line; evidence of leukemic origin by immunoglobulin gene rearrangement.
Saltman D.L., Bansal N.S., Ross F.M., Ross J.A., Turner G., Guy K.
Leuk. Res. 14:381-387(1990).
The leukemia-lymphoma cell line factsbook.";
Drexler H.G.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).