H-EMC-SSHomo sapiens (Human)Cancer cell line
Also known as: HEMC-SS, HEMCSS
🤖 AI SummaryBased on 3 publications
Quick Overview
Human cancer cell line with potential for cancer research.
Detailed Summary
The H-EMC-SS cell line, identified by the ID CVCL_1238, is derived from human cells and is used in cancer research. While the specific tissue of origin and disease context are not specified, the cell line is part of a broader collection of cancer cell lines utilized for studying genomic alterations and cancer biology. Research on this cell line may involve investigating genetic mutations, copy number variations, and their implications in cancer progression. The cell line's characteristics, such as its genetic profile and potential for drug screening, are likely to be explored in various studies to understand cancer mechanisms and develop targeted therapies.
Research Applications
Cancer genomics researchGenomic alteration studiesDrug screening and development
Key Characteristics
Human originPotential for studying cancer mutationsUse in genomic research
Generated on 6/16/2025
Basic Information
| Database ID | CVCL_1238 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Muscle[UBERON:UBERON_0001630] |
Donor Information
| Age | 77 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Extraskeletal myxoid chondrosarcoma |
|---|---|
| Lineage | Bone |
| Subtype | Extraskeletal Myxoid Chondrosarcoma |
| OncoTree Code | EMCHS |
DepMap Information
| Source Type | Sigma-Aldrich |
|---|---|
| Source ID | ACH-001519_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
9
D16S539
9,13
D18S51
16,24
D21S11
30,32.2
D3S1358
15,16
D5S818
10,12
D7S820
8,11
D8S1179
14,17
FGA
21,22
Penta D
9,10
Penta E
10,14
TH01
7,9
TPOX
8
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Pan-cancer proteomic map of 949 human cell lines.";
Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Cancer Cell 40:835-849.e8(2022).
SLFN11 is widely expressed in pediatric sarcoma and induces variable sensitization to replicative stress caused by DNA-damaging agents.
Neale G., Tinkle C.L., Federico S.M., Stewart E.A., Shelat A.A.
Mol. Cancer Ther. 20:2151-2165(2021).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Haber D.A.
Cancer Res. 70:2158-2164(2010).