MPP 89Homo sapiens (Human)Cancer cell line

Also known as: MPP89, MPP-89

🤖 AI SummaryBased on 5 publications

Quick Overview

Human cell line for cancer research, unknown tissue and disease

Detailed Summary

MPP 89 is a human cell line with unknown tissue and disease origins. It is used in cancer research, though specific applications are not detailed in the provided data. The cell line's characteristics, including its genetic and molecular properties, are not fully described, and further research is needed to determine its potential uses in biomedical studies. The lack of detailed information on its origin and specific applications highlights the need for additional characterization to support its utility in scientific investigations.

Generated on 6/17/2025

Basic Information

Database ID	CVCL_1427
Species	Homo sapiens (Human)
Tissue Source	Pleural effusion[UBERON:UBERON_0000175]

Donor Information

Age	67
Age Category	Adult
Sex	Male

Disease Information

Disease	Pleural mesothelioma
Lineage	Pleura
Subtype	Pleural Mesothelioma, Epithelioid Type
OncoTree Code	PLEMESO

DepMap Information

Source Type	ICLC
Source ID	ACH-000319_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin

X,Y

CSF1PO

11,12

D13S317

D16S539

11,13

D5S818

11,12

D7S820

11,12

TH01

TPOX

vWA

Gene Expression Profile

Gene expression levels and statistical distribution

Loading cohorts...

Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

Pan-cancer proteomic map of 949 human cell lines.";

Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

Cancer Cell 40:835-849.e8(2022).

DOI PubMed PMC

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types.

van 't Veer L.J., Butte A.J., Goldstein T., Sirota M.

Nat. Commun. 10:3574.1-3574.11(2019).

DOI PubMed PMC

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

DOI PubMed PMC

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

DOI PubMed PMC

A landscape of pharmacogenomic interactions in cancer.";

Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

Cell 166:740-754(2016).

DOI PubMed PMC

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

DOI PubMed PMC

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

DOI PubMed PMC

Signatures of mutation and selection in the cancer genome.";

Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Nature 463:893-898(2010).

DOI PubMed PMC

Establishment of four new mesothelioma cell lines: characterization by ultrastructural and immunophenotypic analysis.

Mutti L.

Eur. Respir. J. 13:527-534(1999).

DOI PubMed