NH-6Homo sapiens (Human)Cancer cell line

Also known as: Neuroblastoma-6, NH6

🤖 AI SummaryBased on 4 publications

Quick Overview

Human cancer cell line with unknown tissue and disease origins.

Detailed Summary

The NH-6 cell line is a human-derived cancer cell line with unknown tissue and disease origins. It is part of the Cancer Cell Line Encyclopedia (CCLE) and has been characterized in genomic and pharmacological studies. The cell line's genetic and molecular profiles are available, providing insights into its potential applications in cancer research and drug development. However, specific details about its tissue of origin and disease context remain unspecified in the available data.
Generated on 6/17/2025

Basic Information

Database IDCVCL_1606
SpeciesHomo sapiens (Human)
Tissue SourceAdrenal gland[UBERON:UBERON_0002369]

Donor Information

0
Age CategoryPediatric
SexFemale
Subtype FeaturesMYC_Amplified

Disease Information

DiseaseNeuroblastoma
LineagePeripheral Nervous System
SubtypeNeuroblastoma
OncoTree CodeNBL

DepMap Information

Source TypeHSRRB
Source IDACH-000203_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11,12
D13S317
8,13
D16S539
9,11
D5S818
13
D7S820
11
TH01
6,7
TPOX
8,9
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Signatures of mutation and selection in the cancer genome.";

Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.

Nature 463:893-898(2010).

Screening the p53 status of human cell lines using a yeast functional assay.

Mizusawa H., Tanaka N., Koyama H., Namba M., Kanamaru R., Kuroki T.

Mol. Carcinog. 19:243-253(1997).

Neuroblastoma with DNA amplification and rearrangement in the N-myc gene region.

Hiyama E., Hiyama K., Yokoyama T.

Cancer Res. 51:1946-1951(1991).