SW156Homo sapiens (Human)Cancer cell line

Also known as: SW 156, SW-156

🤖 AI SummaryBased on 7 publications

Quick Overview

Human renal cell carcinoma cell line for cancer research.

Detailed Summary

SW156 is a human renal cell carcinoma cell line derived from a kidney tumor. It is used in cancer research to study tumor biology, drug sensitivity, and genetic alterations. The cell line has been characterized for its protein expression profiles and is part of a large dataset of cancer cell lines. SW156 is also noted for its potential in studying the role of PBRM1 in renal cell carcinoma progression. This cell line is part of a comprehensive collection of human tumor cell lines used in various cancer research applications.

Research Applications

Cancer researchProtein expression analysisDrug sensitivity studiesGenetic alteration studies

Key Characteristics

PBRM1 expression analysisProtein marker for renal cell carcinomaPart of a large cancer cell line dataset

Generated on 6/17/2025

Basic Information

Database ID	CVCL_1719
Species	Homo sapiens (Human)
Tissue Source	Kidney[UBERON:UBERON_0002113]

Donor Information

Age	75
Age Category	Adult
Sex	Male

Disease Information

Disease	Renal cell carcinoma
Lineage	Kidney
Subtype	Renal Cell Carcinoma
OncoTree Code	RCC

DepMap Information

Source Type	ATCC
Source ID	ACH-001398_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin

CSF1PO

D13S317

D16S539

10,12

D18S51

D19S433

12,14

D21S11

27,32.2

D2S1338

19,20

D3S1358

D5S818

10,11

D7S820

11,12

D8S1179

FGA

Penta D

10,12

Penta E

7,11

TH01

9.3

TPOX

vWA

Gene Expression Profile

Gene expression levels and statistical distribution

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Full DepMap dataset with combined data across cell lines

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Publications

Pan-cancer proteomic map of 949 human cell lines.";

Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

Cancer Cell 40:835-849.e8(2022).

DOI PubMed PMC

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

DOI PubMed PMC

Characterization of human cancer cell lines by reverse-phase protein arrays.

Liang H.

Cancer Cell 31:225-239(2017).

DOI PubMed PMC

A landscape of pharmacogenomic interactions in cancer.";

Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

Cell 166:740-754(2016).

DOI PubMed PMC

Loss of PBRM1 expression is associated with renal cell carcinoma progression.

Pawlowski R., Muhl S.M., Sulser T., Krek W., Moch H., Schraml P.

Int. J. Cancer 132:E11-E17(2013).

DOI PubMed

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Haber D.A.

Cancer Res. 70:2158-2164(2010).

DOI PubMed PMC

Human urologic cancer cell lines.";

Williams R.D.

Invest. Urol. 17:359-363(1980).

PubMed

Human tumor lines for cancer research.";

Fogh J.

Cancer Invest. 4:157-184(1986).

DOI PubMed

Analysis of established human carcinoma cell lines for lymphoreticular-associated membrane receptors.

Kerbel R.S., Pross H.F., Leibovitz A.

Int. J. Cancer 20:673-679(1977).

DOI PubMed

Absence of HeLa cell contamination in 169 cell lines derived from human tumors.

Fogh J., Wright W.C., Loveless J.D.

J. Natl. Cancer Inst. 58:209-214(1977).

DOI PubMed

Cultivation, characterization, and identification of human tumor cells with emphasis on kidney, testis, and bladder tumors.

Fogh J.

Natl. Cancer Inst. Monogr. 49:5-9(1978).

PubMed

Development of media for isolation and cultivation of human cancer cells.

Leibovitz A.

(In book chapter) Human tumor cells in vitro; Fogh J. (eds.); pp.23-50; Springer; New York; USA (1975).

DOI

Web Resources

tcpaportal.org