TE 441.THomo sapiens (Human)Cancer cell line
Also known as: TE441T, TE-441-T
🤖 AI SummaryBased on 4 publications
Quick Overview
Human cancer cell line with unknown tissue and disease origin.
Detailed Summary
TE 441.T is a human cancer cell line with unknown tissue and disease origins. It is part of the Cancer Cell Line Encyclopedia (CCLE) and has been profiled for genomic and pharmacological data. The cell line is used in research to understand drug sensitivity and predictive modeling of anticancer treatments. Its genomic characteristics include mutations and gene expression profiles that contribute to its utility in studying cancer biology and therapeutic responses.
Research Applications
Drug sensitivity profilingPredictive modeling of anticancer treatmentsGenomic and pharmacological data analysis
Key Characteristics
Genomic mutationsGene expression profilesPharmacological response data
Generated on 6/17/2025
Basic Information
| Database ID | CVCL_1754 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Connective tissue[UBERON:UBERON_0002384] |
Donor Information
| Age | 14 |
|---|---|
| Age Category | Pediatric |
| Sex | Female |
| Race | black_or_african_american |
| Subtype Features | CIC_DUX4 |
Disease Information
| Disease | Rhabdomyosarcoma |
|---|---|
| Lineage | Soft Tissue |
| Subtype | CIC-DUX4 Sarcoma |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000772_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
12
D16S539
11,12
D18S51
13,23
D19S433
12,14
D21S11
29,30
D2S1338
21,22
D3S1358
16,17
D5S818
10,12
D7S820
10
D8S1179
14,15
FGA
23,25
Penta D
2.2,8
Penta E
16
TH01
7,9
TPOX
7,8
vWA
15,16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Pan-cancer proteomic map of 949 human cell lines.";
Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Cancer Cell 40:835-849.e8(2022).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
A landscape of pharmacogenomic interactions in cancer.";
Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.
Cell 166:740-754(2016).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).