C-4-IHomo sapiens (Human)Cancer cell line

Also known as: Hs 636 T, Hs 636.T, C41, C4I, C4 I, C4-1, C4-I, C-4-i, C-4 I, C-4I

AI Summary

No AI-generated summary available for this cell line.

Basic Information

Database IDCVCL_2253
SpeciesHomo sapiens (Human)
Tissue SourceUterus, cervix[UBERON:UBERON_0000002]

Donor Information

Age41
Age CategoryAdult
SexFemale

Disease Information

DiseaseSquamous cell carcinoma of the cervix uteri
LineageCervix
SubtypeCervical Squamous Cell Carcinoma
OncoTree CodeCESC

DepMap Information

Source TypeATCC
Source IDACH-001334_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12
D13S317
11,12
D16S539
11
D18S51
14
D19S433
13,14
D21S11
29,30
D2S1338
23
D3S1358
16,17
D5S818
9,11
D7S820
10,11
D8S1179
14,15
FGA
25
Penta D
9,13
Penta E
19
TH01
9.3
TPOX
10,11
vWA
14
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines

Loading gene expression data...

Publications

Pan-cancer proteomic map of 949 human cell lines.";

Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

Cancer Cell 40:835-849.e8(2022).

Establishment, authenticity, and characterization of cervical cancer cell lines.

Garcia-Carranca A.M., Cerbon-Cervantes M.A., Alcantara-Quintana L.E.

Mol. Cell. Oncol. 9:2078628.1-2078628.10(2022).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

Genomic characterization of human papillomavirus-positive and -negative human squamous cell cancer cell lines.

Frederick M.J., Myers J.N., Pickering C.R., Johnson F.M.

Oncotarget 8:86369-86383(2017).

A landscape of pharmacogenomic interactions in cancer.";

Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

Cell 166:740-754(2016).

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Haber D.A.

Cancer Res. 70:2158-2164(2010).

Smad4 deficiency in cervical carcinoma cells.";

Schwarte-Waldhoff I.

Oncogene 24:810-819(2005).

Long-term cultivation of hypodiploid human tumor cells.";

Auersperg N.

J. Natl. Cancer Inst. 32:135-163(1964).

Chromosome observations on three epithelial-cell cultures derived from carcinomas of the human cervix.

Auersperg N., Hawryluk A.P.

J. Natl. Cancer Inst. 28:605-627(1962).

Identification of microsatellite instability and mismatch repair gene mutations in breast cancer cell lines.

Santibanez-Koref M.F., Schlag P.M., Scherneck S.

Genes Chromosomes Cancer 37:29-35(2003).

Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.

Rousset M., Zweibaum A., Fogh J.

Cancer Res. 41:1165-1170(1981).

Distinction of seventy-one cultured human tumor cell lines by polymorphic enzyme analysis.

Wright W.C., Daniels W.P., Fogh J.

J. Natl. Cancer Inst. 66:239-247(1981).

Histogenetic behavior of tumors. I. Morphologic variation in vitro and in vivo of two related human carcinoma cell lines.

Auersperg N.

J. Natl. Cancer Inst. 43:151-173(1969).

Human tumor lines for cancer research.";

Fogh J.

Cancer Invest. 4:157-184(1986).

Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas.

Durst M., Croce C.M., Gissmann L., Schwarz E., Huebner K.

Proc. Natl. Acad. Sci. U.S.A. 84:1070-1074(1987).

Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines.

Yee C., Krishnan-Hewlett I., Baker C.C., Schlegel R., Howley P.M.

Am. J. Pathol. 119:361-366(1985).

Structure and transcription of human papillomavirus sequences in cervical carcinoma cells.

Stremlau A., zur Hausen H.

Nature 314:111-114(1985).

Absence of HeLa cell contamination in 169 cell lines derived from human tumors.

Fogh J., Wright W.C., Loveless J.D.

J. Natl. Cancer Inst. 58:209-214(1977).

Chromosome analysis and alkaline phosphatase of C41, a cell line of human cervical origin distinct from HeLa.

Herz F., Miller O.J., Miller D.A., Auersperg N., Koss L.G.

Cancer Res. 37:3209-3213(1977).

One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.

Fogh J., Fogh J.M., Orfeo T.

J. Natl. Cancer Inst. 59:221-226(1977).

Tissue typing of cells in culture. III. HLA antigens of established human cell lines. Attempts at typing by the mixed hemadsorption technique.

Espmark J.A., Ahlqvist-Roth L., Sarne L., Persson A.

Tissue Antigens 11:279-286(1978).