COR-L26Homo sapiens (Human)Cancer cell line

Also known as: CORL26

🤖 AI SummaryBased on 3 publications

Quick Overview

Human lung cancer cell line for research

Detailed Summary

COR-L26 is a human lung cancer cell line derived from a patient with small cell carcinoma. It is used in cancer research to study tumor biology, drug sensitivity, and genetic characteristics. The cell line has been characterized for its growth properties, molecular features, and potential applications in preclinical studies. Research on COR-L26 contributes to understanding the mechanisms of lung cancer progression and therapeutic responses.

Research Applications

Cancer biology researchDrug sensitivity testingGenetic and molecular studies
Generated on 6/18/2025

Basic Information

Database IDCVCL_2410
SpeciesHomo sapiens (Human)
Tissue SourceBone marrow[UBERON:UBERON_0002371]

Donor Information

Age CategoryUnknown
SexFemale

Disease Information

DiseaseSmall cell lung cancer
LineageLung
SubtypeSmall Cell Lung Cancer
OncoTree CodeSCLC

DepMap Information

Source TypeSigma-Aldrich
Source IDACH-001046_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
12,13
D13S317
11
D16S539
11,13
D18S51
15
D21S11
28,30
D3S1358
18
D5S818
11,13
D7S820
9,11
D8S1179
11,14
FGA
18,19
Penta D
9,10
Penta E
10,17
TH01
6,9.3
TPOX
8,10
vWA
16,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.

Loewer M., Sahin U., Castle J.C.

Genome Med. 7:118.1-118.7(2015).

A resource for cell line authentication, annotation and quality control.

Neve R.M.

Nature 520:307-311(2015).

A comprehensive transcriptional portrait of human cancer cell lines.

Settleman J., Seshagiri S., Zhang Z.-M.

Nat. Biotechnol. 33:306-312(2015).

Establishment and characterisation of cell lines from patients with lung cancer (predominantly small cell carcinoma).

Watson J.V., Johnson N., Reeve J.G., Bleehen N.M.

Br. J. Cancer 52:495-504(1985).