COR-L32Homo sapiens (Human)Cancer cell line

Also known as: CORL32, Cor L32

🤖 AI SummaryBased on 2 publications

Quick Overview

Human cell line derived from lung cancer, used in cancer research.

Detailed Summary

COR-L32 is a human cell line derived from lung cancer, specifically from a patient with poorly differentiated squamous cell carcinoma. This cell line is part of a collection of cancer cell lines used for in vitro studies, providing a model for investigating the biological characteristics and therapeutic responses of lung cancer. The cell line has been characterized in terms of its growth properties, morphology, and molecular features, contributing to research on cancer biology and drug development. COR-L32 is one of several cell lines established from various types of lung cancer, including small cell and non-small cell carcinomas, and is utilized in studies related to tumor heterogeneity, drug sensitivity, and genetic diversity.

Research Applications

cancer researchdrug developmenttumor heterogeneitygenetic diversitycell line characterization

Key Characteristics

established from lung cancerderived from squamous cell carcinomaused in in vitro studiescharacterized for growth propertiespart of a larger collection of cancer cell lines
Generated on 6/18/2025

Basic Information

Database IDCVCL_2413
SpeciesHomo sapiens (Human)
Tissue SourceBone marrow[UBERON:UBERON_0002371]

Donor Information

Age CategoryUnknown
SexUnknown

Disease Information

DiseaseLung squamous cell carcinoma
LineageLung
SubtypeLung Squamous Cell Carcinoma
OncoTree CodeLUSC

DepMap Information

Source TypeSigma-Aldrich
Source IDACH-001489_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
11
D13S317
8
D16S539
9,11
D18S51
13
D21S11
27,32.2
D3S1358
14,17
D5S818
12
D7S820
8,10
D8S1179
14,15
FGA
21
Penta D
12,13
Penta E
7,10
TH01
7,9.3
TPOX
10
vWA
14
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Pan-cancer proteomic map of 949 human cell lines.";

Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

Cancer Cell 40:835-849.e8(2022).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

A landscape of pharmacogenomic interactions in cancer.";

Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

Cell 166:740-754(2016).

A resource for cell line authentication, annotation and quality control.

Neve R.M.

Nature 520:307-311(2015).

Establishment and characterisation of cell lines from patients with lung cancer (predominantly small cell carcinoma).

Watson J.V., Johnson N., Reeve J.G., Bleehen N.M.

Br. J. Cancer 52:495-504(1985).