HEL 92.1.7Homo sapiens (Human)Cancer cell line
Also known as: HEL9217, HEL-92, HEL-92_1_7, HEL-92-1-7, HEL-92.1.7, HEL92.1.7
🤖 AI SummaryBased on 3 publications
Quick Overview
Human cell line with unknown tissue and disease origin, used in cancer research.
Detailed Summary
HEL 92.1.7 is a human cell line with unknown tissue and disease origins. While the specific tissue of origin and disease association remain unspecified, this cell line is utilized in cancer research. The lack of detailed information on its characteristics and applications highlights the need for further investigation to fully understand its potential in biomedical studies. Researchers may use this cell line to explore various aspects of cancer biology, although specific research applications are not detailed in the available data.
Research Applications
Cancer research
Key Characteristics
Human originUnknown tissue and disease origin
Generated on 6/18/2025
Basic Information
| Database ID | CVCL_2481 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Donor Information
| Additional Information |
|
|---|---|
| Age | 30 |
| Age Category | Adult |
| Sex | Male |
| Race | caucasian |
Disease Information
| Disease | Acute erythroid leukemia |
|---|---|
| Lineage | Myeloid |
| Subtype | Acute Myeloid Leukemia |
| OncoTree Code | AML |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000005_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Met133Lys (c.398T>A) | Homozygous | - | from parent cell line HEL |
| MutationSimple | JAK2 | p.Val617Phe (c.1849G>T) | Homozygous | - | from parent cell line UKE-1 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
10
D13S317
9,11
D16S539
11
D18S51
12,16
D19S433
11,13
D21S11
29,30.2
D2S1338
18,19
D3S1358
15
D5S818
11
D7S820
7
D8S1179
13,15
FGA
22,23
Penta D
11,13
Penta E
13,18
TH01
7
TPOX
11
vWA
14,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
Yang H.H., Koeffler H.P.
BMC Cancer 18:940.1-940.13(2018).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).