HuNS1Homo sapiens (Human)Transformed cell line
Also known as: HUNS1
🤖 AI SummaryBased on 3 publications
Quick Overview
HuNS1 cell line for cancer research and drug testing.
Detailed Summary
The HuNS1 cell line is derived from human tissue and is used in cancer research. It is part of the Cancer Cell Line Encyclopedia (CCLE) and has been utilized in studies related to drug sensitivity and genomic profiling. The cell line's genetic and molecular characteristics make it a valuable tool for understanding cancer biology and developing targeted therapies. However, specific details about its tissue origin, disease type, and cell type are currently unknown, which limits the scope of its applications in certain research areas.
Research Applications
Cancer researchDrug sensitivity testingGenomic profiling
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used in studies of drug response and genomic data
Generated on 6/19/2025
Basic Information
| Database ID | CVCL_2526 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Peripheral blood[UBERON:UBERON_0000178] |
Donor Information
| Age Category | Unknown |
|---|---|
| Sex | Male |
Disease Information
| Disease | Mature B-Cell Neoplasms |
|---|---|
| Lineage | Lymphoid |
| Subtype | Plasma Cell Myeloma |
| OncoTree Code | PCM |
DepMap Information
| Source Type | ATCC |
|---|---|
| Source ID | ACH-000829_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X,Y
CSF1PO
10,12
D13S317
12
D16S539
11
D18S51
14,18
D19S433
15,15.2
D21S11
30,33.2
D2S1338
20,21,22
D3S1358
15,17
D5S818
10,12
D7S820
10
D8S1179
11,14
FGA
24
Penta D
9,12
Penta E
16,17
TH01
9,9.3
TPOX
8
vWA
16,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
Yang H.H., Koeffler H.P.
BMC Cancer 18:940.1-940.13(2018).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).