PE/CA-PJ41 (clone D2)Homo sapiens (Human)Cancer cell line
Also known as: Plaepi 41, PECAPJ41, PE CA PJ41, PE/CA-PJ-41, PE-CA-PJ41-cl D2, PECAPJ41CLONED2, PECAPJ34CLONED2
🤖 AI SummaryBased on 2 publications
PE/CA-PJ41 (D2)
Quick Overview
Human cell line with unknown tissue and disease origin, used in cancer research.
Detailed Summary
The PE/CA-PJ41 (clone D2) cell line is derived from human cells and is utilized in cancer research. However, specific details regarding its tissue of origin, disease association, and cell type remain unknown. This cell line is part of the Cancer Cell Line Encyclopedia (CCLE), which provides comprehensive genomic and pharmacological data for a wide range of cancer cell lines. The CCLE aims to facilitate the identification of genetic and pharmacological predictors of drug sensitivity, contributing to the development of personalized cancer therapies. While the exact characteristics of PE/CA-PJ41 (D2) are not fully detailed, its inclusion in such a large-scale dataset suggests its potential value in understanding cancer biology and drug response mechanisms.
Research Applications
Cancer researchDrug sensitivity profiling
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used for genomic and pharmacological studies
Generated on 6/19/2025
Basic Information
| Database ID | CVCL_2680 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age | 67 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Squamous cell carcinoma of the oral cavity |
|---|---|
| Lineage | Head and Neck |
| Subtype | Oral Cavity Squamous Cell Carcinoma |
| OncoTree Code | OCSC |
DepMap Information
| Source Type | ECACC |
|---|---|
| Source ID | ACH-000732_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | c.920-2A>T (IVS8-2A>T) | Homozygous | Splice acceptor mutation | Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
11,13
D13S317
11,12
D16S539
11,13
D5S818
12
D7S820
9,11
TH01
7
TPOX
8
vWA
15,19
Gene Expression Profile
Gene expression levels and statistical distribution
Loading cohorts...
Full DepMap dataset with combined data across cell lines
Loading gene expression data...
Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).
Oral squamous cell carcinoma invasion is associated with a laminin-5 matrix re-organization but independent of basement membrane and hemidesmosome formation. Clues from an in vitro invasion model.
Berndt A., Hyckel P., Konneker A., Katenkamp D., Kosmehl H.
Invasion Metastasis 17:251-258(1997).