NCC-StC-K140Homo sapiens (Human)Cancer cell line

Also known as: K140, NCCSTCK140, NCCStCK140

🤖 AI SummaryBased on 3 publications

Quick Overview

Human cell line for cancer research, unknown tissue and disease

Detailed Summary

The NCC-StC-K140 cell line is derived from human cells, but specific details about its tissue origin, disease association, and cell type remain unknown. This cell line is part of the broader collection of cancer cell lines used in research, though no specific applications or characteristics are explicitly mentioned in the available data. Further studies would be required to determine its potential use in cancer research and its biological properties.
Generated on 6/19/2025

Basic Information

Database IDCVCL_3055
SpeciesHomo sapiens (Human)
Tissue SourceStomach[UBERON:UBERON_0000945]

Donor Information

Age36
Age CategoryAdult
SexFemale

Disease Information

DiseaseGastric carcinoma
LineageEsophagus/Stomach
SubtypeStomach Adenocarcinoma
OncoTree CodeSTAD

DepMap Information

Source TypeRIKEN
Source IDACH-000110_source

Known Sequence Variations

TypeGene/ProteinDescriptionZygosityNoteSource
MutationSimpleTP53p.Arg248Gln (c.743G>A)UnspecifiedSomatic mutation acquired during proliferationPubMed=20575032

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin
X
CSF1PO
10
D13S317
12
D16S539
12
D5S818
9
D7S820
11,12
TH01
7,9
TPOX
8,11
vWA
14
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines

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Publications

Next-generation characterization of the Cancer Cell Line Encyclopedia.

Sellers W.R.

Nature 569:503-508(2019).

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.

Nature 483:603-607(2012).

Culture of retinoblastoma cells from clinical specimens: growth-promoting effect of 2-mercaptoethanol.

Inomata M., Kaneko A., Saijo N., Tokura S.

J. Cancer Res. Clin. Oncol. 120:149-155(1994).