SKNHomo sapiens (Human)Cancer cell line

🤖 AI SummaryBased on 4 publications

Quick Overview

Human cell line with potential applications in cancer research.

Detailed Summary

The SKN cell line is derived from human tissue and is used in cancer research. It is part of a collection of cell lines that are utilized for various studies, including those related to tumor angiogenesis and genetic diversity. The cell line's characteristics are being explored to understand its role in cancer biology and to support research on health disparities. However, specific details about its tissue origin, disease type, and cell type are currently unknown. Further research is needed to fully characterize the SKN cell line and its potential applications in medical studies.

Research Applications

Cancer researchTumor angiogenesisGenetic diversity studies

Key Characteristics

Human originPotential for cancer studiesUsed in health disparity research

Generated on 6/19/2025

Basic Information

Database ID	CVCL_3167
Species	Homo sapiens (Human)

Donor Information

Age	52
Age Category	Adult
Sex	Female

Disease Information

Disease	Leiomyosarcoma of the corpus uteri
Lineage	Uterus
Subtype	Uterine Leiomyosarcoma
OncoTree Code	ULMS

DepMap Information

Source Type	JCRB
Source ID	ACH-001655_source

Haplotype Information (STR Profile)

Short Tandem Repeat (STR) profile for cell line authentication.

Amelogenin

CSF1PO

10,11

D13S317

D16S539

D18S51

13,15

D21S11

31.2

D3S1358

D5S818

12,13

D7S820

8,12

D8S1179

13,15

FGA

Penta D

Penta E

TH01

TPOX

vWA

Gene Expression Profile

Gene expression levels and statistical distribution

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Full DepMap dataset with combined data across cell lines

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Publications

Pan-cancer proteomic map of 949 human cell lines.";

Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.

Cancer Cell 40:835-849.e8(2022).

DOI PubMed PMC

An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.

Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.

Cancer Res. 79:1263-1273(2019).

DOI PubMed PMC

A landscape of pharmacogenomic interactions in cancer.";

Wessels L.F.A., Saez-Rodriguez J., McDermott U., Garnett M.J.

Cell 166:740-754(2016).

DOI PubMed PMC

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.

Haber D.A.

Cancer Res. 70:2158-2164(2010).

DOI PubMed PMC

Tumor angiogenesis factors produced by cancer cells.";

Ishiwata I., Sudo T., Kiguchi K., Ishikawa H.

Hum. Cell 12:37-46(1999).

PubMed

Effects of feeder cells (human cancer cell lines) on the development of mouse embryos by co-culture.

Ishikawa H.

Hum. Cell 10:237-246(1997).

PubMed

Tissue reconstruction of gynecologic tumor cells in the rotation culture system.

Hashimoto H., Tachibana T., Ishikawa H., Nozawa S.

Hum. Cell 10:175-181(1997).

PubMed

Tumor angiogenic activity of gynecologic tumor cell lines on the chorioallantoic membrane.

Ishiwata I., Ishiwata C., Soma M., Ono I., Nakaguchi T., Ishikawa H.

Gynecol. Oncol. 29:87-93(1988).

DOI PubMed

CA125 production by gynecologic tumors in vitro and its modulation induced by dibutyl cyclic adenosine monophosphate.

Ishiwata I., Ishiwata C., Nozawa S., Ishikawa H.

Asia Oceania J. Obstet. Gynaecol. 12:285-290(1986).

DOI PubMed

Establishment of a human leiomyosarcoma cell line.";

Ishiwata I., Nozawa S., Nagai S., Kurihara S., Mikata A., Okumura H.

Cancer Res. 37:658-664(1977).

PubMed