ZF4Danio rerio (Zebrafish)Spontaneously immortalized cell line
🤖 AI SummaryBased on 1 publications
ZF4 Cell Line
Quick Overview
Zebrafish cell line for research on gene expression and cellular processes.
Detailed Summary
The ZF4 cell line is a zebrafish embryonic fibroblast cell line established from 24-hour post-fertilization (hpf) embryos. It is characterized by its ability to undergo genetic manipulation through lipid-mediated transfection and nucleofection, making it a valuable tool for studying gene expression and cellular responses. Research indicates that ZF4 cells exhibit unique transcriptome profiles compared to adult zebrafish and 24 hpf embryos, with distinct gene expression patterns in response to serum growth factors. These properties suggest potential applications in wound-healing and cancer research. The cell line has been used in studies involving transfection efficiency, stable integration of foreign DNA, and comparative transcriptome analysis, contributing to the understanding of zebrafish cellular mechanisms.
Research Applications
Gene expression analysisTransfection studiesTranscriptome profilingWound-healing researchCancer-related gene expression
Key Characteristics
Genetic stabilityTransfection capabilityUnique transcriptome profileResponse to serum growth factors
Generated on 6/20/2025
Basic Information
| Database ID | CVCL_3275 |
|---|---|
| Species | Danio rerio (Zebrafish) |