KE-97Homo sapiens (Human)Transformed cell line
Also known as: KE97
🤖 AI SummaryBased on 3 publications
Quick Overview
KE-97 cell line for cancer research and drug development
Detailed Summary
KE-97 is a human cell line used in cancer research, particularly in the study of gastric cancer. It is part of the Cancer Cell Line Encyclopedia (CCLE) and has been utilized in genomic and transcriptomic analyses to understand cancer biology and therapeutic responses. The cell line is known for its role in identifying genetic and molecular characteristics associated with cancer progression and drug sensitivity. Research involving KE-97 has contributed to the identification of key mutations and pathways that may be targeted for therapeutic intervention.
Research Applications
Cancer researchGenomic analysisTranscriptomic analysisDrug development
Key Characteristics
Part of CCLEUsed in gastric cancer studiesIdentified genetic mutationsStudied for drug sensitivity
Generated on 6/20/2025
Basic Information
| Database ID | CVCL_3386 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age | 52 |
|---|---|
| Age Category | Adult |
| Sex | Male |
Disease Information
| Disease | Mature B-Cell Neoplasms |
|---|---|
| Lineage | Lymphoid |
| Subtype | Plasma Cell Myeloma |
| OncoTree Code | PCM |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000167_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,12
D13S317
8
D16S539
11
D18S51
16,17
D19S433
12,14
D21S11
31,32.2
D2S1338
20
D3S1358
15
D5S818
11,13
D7S820
8,12
D8S1179
10,15
FGA
18,24
Penta D
9,13
Penta E
5
TH01
7,9
TPOX
9,11
vWA
16,18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
Profiling the B/T cell receptor repertoire of lymphocyte derived cell lines.
Yang H.H., Koeffler H.P.
BMC Cancer 18:940.1-940.13(2018).
A resource for cell line authentication, annotation and quality control.
Neve R.M.
Nature 520:307-311(2015).
Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer.
Firestein R., Zhang Z.-M.
Nat. Commun. 5:3830.1-3830.8(2014).
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
Nature 483:603-607(2012).