JHUEM-1Homo sapiens (Human)Cancer cell line
Also known as: JHUEM1
🤖 AI SummaryBased on 2 publications
Quick Overview
Human cell line with unknown tissue and disease origins.
Detailed Summary
JHUEM-1 is a human cell line with no available information on its tissue of origin, disease association, or specific cell type. The lack of detailed characterization limits its immediate applicability in research. However, its inclusion in large-scale genomic and pharmacological studies, such as the Cancer Cell Line Encyclopedia (CCLE), suggests potential for future investigations into genetic and drug response profiles. Further research is needed to determine its biological properties and relevance to cancer studies.
Research Applications
Genomic and pharmacological profilingDrug sensitivity and resistance studies
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Potential for predictive modeling of anticancer drug sensitivity
Generated on 6/21/2025
Basic Information
| Database ID | CVCL_4655 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Endometrium[UBERON:UBERON_0001295] |
Donor Information
| Age | 56 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
Disease Information
| Disease | Endometrial adenocarcinoma |
|---|---|
| Lineage | Uterus |
| Subtype | Endometrial Carcinoma |
| OncoTree Code | UCEC |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000928_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | PTEN | p.Arg233Ter (c.697C>T) | Heterozygous | - | PubMed=28683746, PubMed=24042735 |
| MutationSimple | PIK3CA | p.Glu542Lys (c.1624G>A) | Unspecified | - | PubMed=31541927 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,14
D13S317
8
D16S539
9,10
D5S818
11,12
D7S820
12,13
TH01
6
TPOX
7,8
vWA
17,18,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).