JHUEM-2Homo sapiens (Human)Cancer cell line
Also known as: JHUEM2
🤖 AI SummaryBased on 3 publications
Quick Overview
Human cell line with unknown tissue and disease origin, used in cancer research.
Detailed Summary
JHUEM-2 is a human cell line with unknown tissue and disease origins. It is part of the Cancer Cell Line Encyclopedia (CCLE) and has been profiled for genomic and pharmacological data. This cell line is utilized in studies related to cancer biology and drug sensitivity, contributing to the understanding of anticancer drug responses. The CCLE provides extensive genomic and pharmacological annotations, enabling researchers to explore predictors of drug sensitivity and resistance. JHUEM-2's inclusion in such large-scale datasets highlights its value in preclinical cancer research and the development of targeted therapies.
Research Applications
Cancer biology researchDrug sensitivity profilingGenomic and pharmacological annotation
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Profiled for genomic and pharmacological dataUsed in studies of anticancer drug responses
Generated on 6/21/2025
Basic Information
| Database ID | CVCL_4656 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Endometrium[UBERON:UBERON_0001295] |
Donor Information
| Age | 62 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
Disease Information
| Disease | Endometrial adenocarcinoma |
|---|---|
| Lineage | Uterus |
| Subtype | Endometrial Carcinoma |
| OncoTree Code | UCEC |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000909_source |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
9
D16S539
9,10
D5S818
11,14
D7S820
11
TH01
7,9
TPOX
8,9,11
vWA
14
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).