JHUEM-7Homo sapiens (Human)Cancer cell line
Also known as: JHUEM7
🤖 AI SummaryBased on 3 publications
Quick Overview
Human cancer cell line with unknown tissue and disease origins.
Detailed Summary
JHUEM-7 is a human cancer cell line with unknown tissue and disease origins. It is part of the Cancer Cell Line Encyclopedia (CCLE) and has been characterized in genomic and pharmacological studies. The cell line's genetic and molecular profiles are available, providing insights into its potential use in cancer research and drug development. Further research is needed to determine its specific tissue of origin and disease association.
Research Applications
Genomic and pharmacological profilingCancer research and drug development
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Available genomic and molecular profiles
Generated on 6/21/2025
Basic Information
| Database ID | CVCL_4658 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Endometrium[UBERON:UBERON_0001295] |
Donor Information
| Age | 58 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
Disease Information
| Disease | Endometrial adenocarcinoma |
|---|---|
| Lineage | Uterus |
| Subtype | Endometrial Carcinoma |
| OncoTree Code | UCEC |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000993_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | ARID1A | p.Arg1989Ter (c.5965C>T) | Homozygous | - | Unknown, Unknown |
| MutationSimple | APC | p.Arg2204Ter (c.6610C>T) | Heterozygous | - | Unknown, Unknown |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10,13
D13S317
10,11
D16S539
9,13
D5S818
11
D7S820
10
TH01
7,9.3
TPOX
8
vWA
15,17
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).