LMSUHomo sapiens (Human)Cancer cell line
🤖 AI SummaryBased on 3 publications
Quick Overview
Human cancer cell line with unknown tissue and disease origin.
Detailed Summary
The LMSU cell line is derived from human cells and is used in cancer research. However, specific details about its tissue of origin, disease type, and cell type are not available. This cell line is part of the Cancer Cell Line Encyclopedia (CCLE) and has been profiled for genomic and pharmacological data. Research involving LMSU focuses on understanding cancer biology and drug sensitivity, contributing to the development of targeted therapies. Further studies are needed to fully characterize its properties and applications.
Research Applications
Cancer biology researchDrug sensitivity profilingGenomic and pharmacological data analysis
Key Characteristics
Part of the Cancer Cell Line Encyclopedia (CCLE)Used for understanding cancer drug responseProfiled for genomic and pharmacological data
Generated on 6/21/2025
Basic Information
| Database ID | CVCL_4849 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Lymph node[UBERON:UBERON_0000029] |
Donor Information
| Age | 27 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Gastric carcinoma |
|---|---|
| Lineage | Esophagus/Stomach |
| Subtype | Stomach Adenocarcinoma |
| OncoTree Code | STAD |
DepMap Information
| Source Type | RIKEN |
|---|---|
| Source ID | ACH-000255_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Arg175His (c.524G>A) | Unspecified | Somatic mutation acquired during proliferation | from parent cell line YCC-3 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
12
D13S317
12
D16S539
10
D5S818
11,12
D7S820
11
TH01
6,7
TPOX
9
vWA
16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Quantitative proteomics of the Cancer Cell Line Encyclopedia.";
Sellers W.R., Gygi S.P.
Cell 180:387-402.e16(2020).
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).