NP-8Homo sapiens (Human)Cancer cell line
Also known as: Case 1, NP8, NP 8
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_4W66 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Brain, left temporal lobe[UBERON:UBERON_0002808] |
Donor Information
| Age | 38 |
|---|---|
| Age Category | Adult |
| Sex | Female |
Disease Information
| Disease | Glioblastoma |
|---|---|
| Lineage | CNS/Brain |
| Subtype | Glioblastoma |
| OncoTree Code | GB |
DepMap Information
| Source Type | JCRB |
|---|---|
| Source ID | ACH-001611_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | CDKN2A | p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T) | Unspecified | - | PubMed=11787853 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10
D13S317
8,11
D16S539
11
D18S51
13
D21S11
28,29
D3S1358
15,17
D5S818
10,12
D7S820
11,12
D8S1179
13
FGA
22,23
Penta D
11,12
Penta E
12,18
TH01
9
TPOX
8,9
vWA
18
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Frequent and variable abnormalities in p14 tumor suppressor gene in glioma cell lines.
Washiyama K., Kumanishi T., Uematsu Y., Itakura T.
Brain Tumor Pathol. 25:9-17(2008).
Rare-type mutations of MMAC1 tumor suppressor gene in human glioma cell lines and their tumors of origin.
Washiyama K., Kumanishi T.
Jpn. J. Cancer Res. 90:934-941(1999).