TC-205Homo sapiens (Human)Cancer cell line
Also known as: TC205
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_4Z31 |
|---|---|
| Species | Homo sapiens (Human) |
Donor Information
| Age Category | Pediatric |
|---|---|
| Sex | Unknown |
| Subtype Features | EWS-FEV |
Disease Information
| Disease | Bone sarcoma |
|---|---|
| Lineage | Bone |
| Subtype | Ewing Sarcoma |
| OncoTree Code | ES |
DepMap Information
| Source Type | Academic lab |
|---|---|
| Source ID | ACH-001431_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| Gene fusion | EWSR1 | EWSR1-FEV, EWS-FEV | - | EWSR1 exon 7 fused to FEV exon 3 | DOI=10.5282/edoc.27750 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10
D13S317
8,10
D16S539
13
D18S51
15
D19S433
14,17.2
D21S11
28,30
D2S1338
17,25
D3S1358
17
D5S818
12
D7S820
10,12
D8S1179
12,13
FGA
21,23
TH01
8,9
TPOX
8,11
vWA
15,16
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
The genomic landscape of the Ewing sarcoma family of tumors reveals recurrent STAG2 mutation.
Catchpoole D., Llombart-Bosch A., Waldman T., Khan J.
PLoS Genet. 10:E1004475-E1004475(2014).
Systematic multi-omics profiling of Ewing sarcoma cell lines.";
Orth M.F.
Thesis PhD (2021); Ludwig Maximilians University of Munich; Munich; Germany.