SNU-1033Homo sapiens (Human)Cancer cell line
Also known as: SNU1033
AI Summary
No AI-generated summary available for this cell line.
Basic Information
| Database ID | CVCL_5002 |
|---|---|
| Species | Homo sapiens (Human) |
| Tissue Source | Rectum[UBERON:UBERON_0001052] |
Donor Information
| Age | 45 |
|---|---|
| Age Category | Adult |
| Sex | Female |
| Race | asian |
Disease Information
| Disease | Rectal adenocarcinoma |
|---|---|
| Lineage | Bowel |
| Subtype | Rectal Adenocarcinoma |
| OncoTree Code | READ |
DepMap Information
| Source Type | KCLB |
|---|---|
| Source ID | ACH-000286_source |
Known Sequence Variations
| Type | Gene/Protein | Description | Zygosity | Note | Source |
|---|---|---|---|---|---|
| MutationSimple | TP53 | p.Pro190Leu (c.569C>T) | Hemizygous | - | from parent cell line VACO 8 |
| MutationSimple | KRAS | p.Gly12Asp (c.35G>A) | Unspecified | - | PubMed=29786757 |
Haplotype Information (STR Profile)
Short Tandem Repeat (STR) profile for cell line authentication.
Amelogenin
X
CSF1PO
10
D10S1248
13,15
D12S391
18,21
D13S317
10
D16S539
9
D18S51
13
D19S433
13,14
D1S1656
13
D21S11
29,30
D22S1045
17
D2S1338
18,26
D2S441
10,12
D3S1358
14,17
D5S818
13
D7S820
11,12
D8S1179
12,13
FGA
23
Penta D
11,12
Penta E
11
TH01
9
TPOX
11
vWA
17,19
Gene Expression Profile
Gene expression levels and statistical distribution
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Full DepMap dataset with combined data across cell lines
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Publications
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Sellers W.R.
Nature 569:503-508(2019).
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
Cancer Res. 79:1263-1273(2019).
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Loewer M., Sahin U., Castle J.C.
Genome Med. 7:118.1-118.7(2015).
The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.
Linnebacher M., Cordero F., Di Nicolantonio F., Bardelli A.
Nat. Commun. 6:7002.1-7002.10(2015).
Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.
Ku J.-L., Yoon K.-A., Kim D.-Y., Park J.-G.
Eur. J. Cancer 35:1724-1729(1999).